Pediatric Endocrinology. A Clinical Guide. 2nd Edition

نویسنده

  • Margretta R. Seashore
چکیده

ment of cancer are better understood than any genes which relate to the physical phenotype of Down syndrome. The causes of the mental retardation remain unelucidated, but the Alzheimer disease-related genes are discussed as possibilities. The creation of mouse models and the study of the existing mouse model based on partial trisomy of mouse chromosome 16 offer many exciting avenues for research. These are discussed in the third section of the symposium. If there is any hope for therapy of any of the chromosomal aneuploidies, studies of such animal models will prove crucial. This book will be useful to geneticists and others interested in Down syndrome and the scientific progress being made to understand it, as well as to those interested in studying the relationship between aneuploidy and phenotype in other chromosomal abnormalities. It will be useful to those interested in other genes which map to chromosome 21 as well. The volume serves both as a review and an overview of the field. Knowledge of modern molecular genetics concepts and techniques is assumed. The illustrations are clear, and, while there are no glossy photographs, the photographs which are presented reproduce well.

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عنوان ژورنال:
  • The Yale Journal of Biology and Medicine

دوره 64  شماره 

صفحات  -

تاریخ انتشار 1991